Role of CD4+CD25hiCD127lo/-FoxP3+ regulatory T lymphocytes in the pathogenesis of Behçet’s disease in children
نویسندگان
چکیده
Patients and methods 19 patients with active BD (group A) and 8 patients with inactive BD (group B) were compared with 25 healthy controls (group C). Percentages of blood CD4 +CD127-CD25hiFoxP3+ Tregs and other T/B and NK cells subpopulations were nalayzed by flow cytometry. The frequency of IL-17A and IFN-g producing T cells was analyzed by flow cytometer from PBMC after 4 hours stimulation with PMA-ionomycin. We measured serum cytokines by Luminex and ELISA. We compared the 3 groups by using the Wilcoxon-Rank-signed test. Values were expressed as mean and median.
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عنوان ژورنال:
دوره 9 شماره
صفحات -
تاریخ انتشار 2011